Tier 3 Drug Shortages

Tier 3 drug shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Impact is based on low availability of alternative supplies, ingredients or therapies. The Tier Assignment Committee (TAC), composed of federal and provincial/territorial governments, healthcare professionals, and industry stakeholders, makes recommendations on the tier assignment of drug shortages. The TAC assessment includes:

  • a review of the information gathered on the shortage issue, and
  • a thorough discussion on its potential impact and next steps.

Below are the newest and most recently updated active ingredients that have been designated as Tier 3 shortages. Click on the active ingredient to see a list of the associated Tier 3 drug shortage and/or discontinuation reports.

Active Ingredient

21 active ingredients found

Alprostadil Sterile Solution

solution

ASPARAGINASE - ERWINASE

powder for solution

Calcium Gluconate Injection

solution

Continuous Renal Replacement Therapy Solutions

solution

Decitabine/Cedazuridine

tablet

HYDRALAZINE INJECTION

solution

HYDROCORTISONE

tablet

LEVOFLOXACIN INJECTION

solution

Lurbinectedin

powder

MEDROXYPROGESTERONE ACETATE

suspension

Methotrimeprazine Hydrochloride Injection

solution

MORPHINE SULFATE

capsule (sustained-release)

MOXIFLOXACIN INJECTION

solution

Papaverine Hydrochloride Injection

liquid

PROPYLTHIOURACIL

tablet

Remifentanil Hydrochloride Injection

powder for solution

SARILUMAB

solution

Sodium Chloride 0.9% USP Injectable - Diluent

solution

SODIUM THIOSULFATE

powder for solution

Sterile Water for Injection

solution

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