Tier 3 Drug Shortages
Tier 3 drug shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Impact is based on low availability of alternative supplies, ingredients or therapies. The Tier Assignment Committee (TAC), composed of federal and provincial/territorial governments, healthcare professionals, and industry stakeholders, makes recommendations on the tier assignment of drug shortages. The TAC assessment includes:
- a review of the information gathered on the shortage issue, and
- a thorough discussion on its potential impact and next steps.
Below are the newest and most recently updated active ingredients that have been designated as Tier 3 shortages. Click on the active ingredient to see a list of the associated Tier 3 drug shortage and/or discontinuation reports.
Active Ingredient
21 active ingredients found
Alprostadil Sterile Solution
solution |
ASPARAGINASE - ERWINASE
powder for solution |
Calcium Gluconate Injection
solution |
Continuous Renal Replacement Therapy Solutions
solution |
Decitabine/Cedazuridine
tablet |
HYDRALAZINE INJECTION
solution |
HYDROCORTISONE
tablet |
LEVOFLOXACIN INJECTION
solution |
Lurbinectedin
powder |
MEDROXYPROGESTERONE ACETATE
suspension |
Methotrimeprazine Hydrochloride Injection
solution |
MORPHINE SULFATE
capsule (sustained-release) |
MOXIFLOXACIN INJECTION
solution |
Papaverine Hydrochloride Injection
liquid |
PROPYLTHIOURACIL
tablet |
Remifentanil Hydrochloride Injection
powder for solution |
SARILUMAB
solution |
Sodium Chloride 0.9% USP Injectable - Diluent
solution |
SODIUM THIOSULFATE
powder for solution |
Sterile Water for Injection
solution |