Tier 3 Drug Shortages

Tier 3 drug shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Impact is based on low availability of alternative supplies, ingredients or therapies. The Tier Assignment Committee (TAC), composed of federal and provincial/territorial governments, healthcare professionals, and industry stakeholders, makes recommendations on the tier assignment of drug shortages. The TAC assessment includes:

  • a review of the information gathered on the shortage issue, and
  • a thorough discussion on its potential impact and next steps.

Below are the newest and most recently updated active ingredients that have been designated as Tier 3 shortages. Click on the active ingredient to see a list of the associated Tier 3 drug shortage and/or discontinuation reports.

Active Ingredient

28 active ingredients found

ACETYLCHOLINE CHLORIDE

powder for solution

ACETYLCYSTEINE

solution

Amiodarone Injection

liquid

Amoxicillin and Clavulanic Acid Oral Suspensions

powder for suspension

Amoxicillin Oral Suspensions

powder for suspension

Amoxicillin Oral Suspensions

granules for suspension

ASPARAGINASE - ERWINASE

powder for solution

Azithromycin – Oral Suspension

powder for suspension

CARBACHOL

solution

Cefprozil – Oral Suspension

powder for suspension

Cefuroxime – Oral Suspension

granules for suspension

Cephalexin – Oral Suspension

powder for suspension

Clarithromycin – Oral Suspension

granules for suspension

CROMOLYN SODIUM

capsule

Eluxadoline

tablet

Eptifibatide Injection

solution

FLUDARABINE PHOSPHATE

tablet

HALOPERIDOL

tablet

HYDRALAZINE INJECTION

solution

Iodixanol

solution

Iodixanol

solution

LORAZEPAM

solution

Methotrimeprazine Hydrochloride Injection

solution

Ophthalmic Steroids - Dexamethasone 0.1%

suspension

Ophthalmic Steroids - Prednisolone 1%,

suspension

Ophthalmic Steroids- Difluprednate 0.05%.

emulsion

Thallium, Thallous Chloride TI-201 Injection

solution

Tocilizumab, subcutaneous format

solution

Vigabatrin, powder for oral solution

powder for solution

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