Tier 3 Drug Shortages

Tier 3 drug shortages are those that have the greatest potential impact on Canada's drug supply and health care system. Impact is based on low availability of alternative supplies, ingredients or therapies. The Tier Assignment Committee (TAC), composed of federal and provincial/territorial governments, healthcare professionals, and industry stakeholders, makes recommendations on the tier assignment of drug shortages. The TAC assessment includes:

  • a review of the information gathered on the shortage issue, and
  • a thorough discussion on its potential impact and next steps.

Below are the newest and most recently updated active ingredients that have been designated as Tier 3 shortages. Click on the active ingredient to see a list of the associated Tier 3 drug shortage and/or discontinuation reports.

Active Ingredient

22 active ingredients found

ALDESLEUKIN

powder for solution

Alprostadil Sterile Solution

solution

Apomorphine Hydrochloride

solution

Apomorphine Hydrochloride

film, soluble

ARGATROBAN

solution

ASPARAGINASE - ERWINASE

powder for solution

Carbamazepine

tablet (extended-release)

CHOLESTYRAMINE RESIN

powder for suspension

COLESEVELAM HYDROCHLORIDE

tablet

COLESEVELAM HYDROCHLORIDE

powder for suspension

COLESTIPOL

granules

DEXTROSE INJECTION

solution

DOXORUBICIN HYDROCHLORIDE

suspension

Eluxadoline

tablet

Epinephrine injection

solution

GLUCAGON

powder for solution

HYDRALAZINE INJECTION

solution

IDARUBICIN HYDROCHLORIDE

solution

LITHIUM CARBONATE

capsule

LITHIUM CARBONATE

tablet (extended-release)

Methotrexate

solution

Pantoprazole Sodium for Injection

powder for solution

PEGASPARGASE

solution

PRAZOSIN

tablet

TAMSULOSIN HYDROCHLORIDE

capsule (sustained-release)

TAMSULOSIN HYDROCHLORIDE

tablet (extended-release)

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